Computational Biology of RNA Processing

Roderic Guigó

Research and Interests

Dr. Guigó is interested in the mechanisms of recognition, processing and evolution of the main signals involved in gene specification in genomic sequences, such as promoter elements, splice sites and translation initiation sites. In addition to clarifying these mechanisms, a significant part of his activities focuses on the development of novel software that can predict genes and annotation in genomic sequences.  His group also actively participates in the analysis of many eukaryotic genomes and it is involved in a number of projects, including the NIH-funded ENCODE and GTEx projects, and the European Blueprint projects.

Identifying gene specifications in genomic sequences and their specific signal mechanisms is a paramount step for improving diagnosis and treatment of diseases.