The Charité Entrepreneurship Summit attracts annually 400+ international entrepreneurs, scientists, investors, and healthcare industry professionals. This international and cross-disciplinary event offers a unique platform for building new partnerships that will transform the life sciences and the healthcare industry. The 2016 Edition, “Rethink & Transform healthcare”, will feature highly relevant topics, such as the digitalization of health care, the role of open innovation in dramatically improving drug discovery, the prospects of genome editing and healthy aging, the influence of women in changing the healthcare ecosystem, the growing understanding of the impact of gender differences on research and the practice of medicine, and the importance of delivering value-based medicine.