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Title: squamous cell carcinoma evade the tumor surveillance
Ref: SAB-0028
Author: STEFANIA MEJETTA
CRG Group: Epithelial Homeostasis and Cancer - Salvador Aznar-Benitah
Size: 800 x 800
Description: Human squamous cell carcinoma cell (Blu) develop a full-grown tumor after xenotranplantation. The structure of the tumor is defined by the expression of the basal marker alpha6-integrin (red). Many cancer cells, especially at the leading edge of the tumor, express the "don''t eat me" signal CD47 to evade the immunosurveillance operated by macrophages.
