Research and Interests
To what extent is it possible to predict phenotypic differences amongst individuals from their completely sequenced genomes? Dr. Lehner’s research focuses on combining genetic information with phenotypic predictors to understand how differences between individuals originate in the interaction between genetic, environmental, life history, parental and stochastic sources of variation.
Further understanding how differences between individual originate, will provide better prediction of disease risks and improved treatment outcomes for patients.
Expertise and Capabilities
Dr. Lehner is a world-renowned expert in bioinformatics and systems biology. His group has expertise in:
- Analysis of cancer genomes and exomes;
- C. elegans and yeast genetics and genomics;
- Big data;
- Machine learning;
- Imaging-based screening;
- Deep mutational scanning.
To know more about the group please click here.