Design of Biological Systems
Luis Serrano
Research and Interests
Dr. Serrano aims at a quantitative understanding of biological systems to an extent that one is able to predict systemic features with the hope to rational design and modify their behavior. This applies to any system comprising biological components that is more than the mere sum of its components, or, in other words, the addition of the individual components results in systemic properties that could not have been predicted by considering the components individually. By achieving this objective, Serrano aims at new global understanding and treatment of human diseases in which the target will not be a single molecule but a network.
Within this context, the group runs several and distinct projects that range from the large-scale quantitative analyses of Mycoplasma pneumonia and ways to engineer it into a (living) vehicle for the treatment of various human and animal disorders, to the quantitative systems analyses of mammalian signaling with a focus on the Erk and Erb pathways, etc.
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The aim of the CRG photo gallery is to provide an overview of our scientists’ research activities through the images generated in the course of their research projects.
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Title: Plastic Cells
Ref: LS-0010
Author: Martin Gigirey
Size: 800 x 800
Description: Saos-2 cells looking for each other (gelatin covered)
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The aim of the CRG photo gallery is to provide an overview of our scientists’ research activities through the images generated in the course of their research projects.
All our images are available on demand in digital form with higher quality for for-profit and any other uses. For any of these requests please contact us.
Title: Nucleus fellowship
Ref: LS-0009
Author: Martin Gigirey
Size: 800 x 598
Description: The migration of nucleus from the cell
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The aim of the CRG photo gallery is to provide an overview of our scientists’ research activities through the images generated in the course of their research projects.
All our images are available on demand in digital form with higher quality for for-profit and any other uses. For any of these requests please contact us.
Title: One
Ref: LS-0007
Author: Julia Burnier
Size: 800 x 800
Description: This is one cell. One of a million cultured in one well of one plate. The tightly regulated system in place to produce each cell is truly amazing. What’s more amazing is how little we actually know about how these cells are perfectly replicated, each with all the components to make it survive, grow, and reproduce. Each pixel of this image represents an unknown, a mysterious and magical door that will surely open to many new unfamiliar worlds.
Explore CRG Images
The aim of the CRG photo gallery is to provide an overview of our scientists’ research activities through the images generated in the course of their research projects.
All our images are available on demand in digital form with higher quality for for-profit and any other uses. For any of these requests please contact us.
Title: Order
Ref: LS-0006
Author: Julia Burnier
Size: 800 x 800
Description: These cells were taken out of their natural environment. They have been grown on plastic, manipulated with dozens of chemicals, processed with man-made reagents, and finally viewed through a machine that allows us to assess their “natural” behavior. Even so, these cells revert to order – their basic need to group in an organized natural way perseveres our unnatural attempts to change them.
Explore CRG Images
The aim of the CRG photo gallery is to provide an overview of our scientists’ research activities through the images generated in the course of their research projects.
All our images are available on demand in digital form with higher quality for for-profit and any other uses. For any of these requests please contact us.
Title: Crowded
Ref: LS-0004
Author: Julia Burnier
Size: 800 x 800
Description: Cells cannot survive alone. It seems that they are most powerful when in abundance and will therefore continue to produce offspring while conditions permit. However, overconfluency also has its perils. When there are too many of them, cells seek a limited food source that cannot sustain the entire population. They begin to have toxic effects on each other and eventually, only those that have more space, more food, and a better location in the population survive. Sound familiar?
Explore CRG Images
The aim of the CRG photo gallery is to provide an overview of our scientists’ research activities through the images generated in the course of their research projects.
All our images are available on demand in digital form with higher quality for for-profit and any other uses. For any of these requests please contact us.
Title: Antigen-Antibody binding on SAOS-2 cells
Ref: LS-0002
Author: Martin Gigirey & Raul Gómez
Size: 800 x 800
Description: Immunofluorescence on Osteosarcoma cells.Over-expressed protein in a tumoral cell detected by target Antibody and, indirectly, by AlexaFluor 488 (green). Nucleus are labeled with Hoechst 33342 (blue)and tubulin with AlexaFluor 568 (red).
Explore CRG Images
The aim of the CRG photo gallery is to provide an overview of our scientists’ research activities through the images generated in the course of their research projects.
All our images are available on demand in digital form with higher quality for for-profit and any other uses. For any of these requests please contact us.
Title: Antigen-Antibody binding on HeLa cells
Ref: LS-0001
Author: Martin Gigirey & Renza Roncarati
Size: 800 x 800
Description: Immunofluorescence on HeLa cells.Over-expressed protein in a tumoral cell detected by target Antibody and, indirectly, by AlexaFluor 488 (green). Nucleus are labeled with Hoechst 33342 (blue)and tubulin with AlexaFluor 568 (red).
Explore CRG Images
The aim of the CRG photo gallery is to provide an overview of our scientists’ research activities through the images generated in the course of their research projects.
All our images are available on demand in digital form with higher quality for for-profit and any other uses. For any of these requests please contact us.
Title: Vision
Ref: LS-0008
Author: Julia Burnier
Size: 800 x 800
Description: Cells, like our eyes, sense information and produce snapshots of their environment, thereby assessing their position in space. Cells use this information to decide on their next move, to regulate their machinery for the appropriate behaviour. In fact, much of what we try to uncover in research is based on how cells respond to what they “see”.
Explore CRG Images
The aim of the CRG photo gallery is to provide an overview of our scientists’ research activities through the images generated in the course of their research projects.
All our images are available on demand in digital form with higher quality for for-profit and any other uses. For any of these requests please contact us.
Title: Tree of Life
Ref: LS-0005
Author: Julia Burnier
Size: 800 x 800
Description: A tree begins with a seed, in which cells divide to produce the roots, the trunk, the leaves, and finally an immense living entity that not only is vital to our existence but decorates our world. How fitting that this cluster of stem cells illustrated that thought so clearly.
